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Local scientists invents novel DNA testing technology to raise test accuracy
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LOCAL scientists invented a novel DNA testing technology, which can raise the accuracy of normal DNA testing and reduce the rate of false positive during clinical diagnosis.
The Low-temperature closed nested PCR, or polymerase chain reaction, is a technique used in molecular biology which can be used in diagnosis and monitoring of diseases and other fields like agriculture and forensics needing DNA testing, said scientists from Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences under Chinese Academy of Sciences.
“Though PCR is widely used in clinical practice, it may have certain fake positive results,” said Hong Guofan, who leads the new measure development. “Our new PCR measure brings down the temperature during testing by 10 to 15 degree Celsius. The low temperature can greatly ensure accuracy and prevent fake positive.”
The new PCR has been tested among more than 1000 patients and showed better results than normal PCR, scientists said.
The new technology has received intellectual property rights and is given to a pharmaceutical company for diagnosis kit development.
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