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Website to monitor drug-induced liver injury set up in city

IMPROPER use of some traditional Chinese medicine, health tonics and overexposure to daily chemicals like hair dye can threaten the liver, medical experts said over the weekend as China’s first online platform collecting and studying drug-induced liver injury was established in the city.

The website will serve as a database for patients, doctors and pharmacists to report adverse reactions to the liver so that experts can weed out medicines that may damage the vital organ. So far, data on hundreds of medicines, TCM and health tonics known to damage the liver are available online for professionals and the public.

Drug-induced liver injury (DILI) is a common cause of prolonged hospitalization, and many failures or withdrawals from the market of new drugs are due to it. In the United States, drug-induced liver injury is the cause of at least 10 percent of hospitalized patients with acute liver injury as well as over 50 percent with acute liver failure.

In China, awareness on such injury has just started.

“Based on the website, we will carry out China’s own epidemiological research on DILI,” said Dr Mao Yimin from Renji Hospital and chief of the website. “It is important to promote the knowledge of DILI among both doctors and the public. The Food and Drug Administration also can have an important source to monitor liver injuries caused by marketed medicines.”


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