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November 23, 2016

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Chinese findings on Zika

CHINESE scientists have revealed that the Zika virus caused male infertility in mice, indicating similar damage to humans.

The study was carried out by teams led by Li Xiangdong from China Agricultural University and Gao Fu from the Institute of Microbiology of Chinese Academy of Sciences. It was published online by Cell, an academic journal.

The joint study shows that Zika virus can cross the blood-testes-barrier under certain conditions such as immunodeficiency, and infect the reproductive tract in male mice. Acute inflammation of the testes was observed from 8 days after infection along with decreased levels of testosterone, with symptoms persisting 16 days after infection.

At 30 days after infection, a breakdown in the morphology of the testes and disruption of the seminal vesicles can be observed, resulting in completely atrophied testes and seminal vesicles by 60 days after infection.

Scientists were realizing the harm of Zika virus on humans might be more severe than had been thought, said Gao.


 

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