Cases of advanced breast cancer rises
Source: Agencies |
February 28, 2013, Thursday
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Print Edition
Print Edition
MORE young women are being diagnosed with advanced, metastatic breast cancer than were three decades ago, according to a US study, with the metastatic breast cancer rate rising about 2 percent each year.
Yet the overall rate of cancers in that group is still small. One in 173 women will develop breast cancer before she turns 40, said researchers, but the prognosis tends to be worse for younger patients.
The study, led by Rebecca Johnson at Seattle Children's Hospital and University of Washington, found that the rate of metastatic breast cancer in particular rose about 2 percent each year between 1976 and 2009 among younger women.
"We think that the likelihood is that since this change has been so marked over just a couple of decades, that it's something external, a modifiable lifestyle-related risk factor or perhaps an environmental toxic exposure, but we don't know what," Johnson said.
One possibility is that overeating and lack of exercise are driving up early-life metastatic breast cancer rates, she added. Or, the use of hormonal birth control could play a role.
But Johnson also pushed for more research into the potential effects of hormones in meat or plastic in bottles, for example.
Johnson's team found that the number of early breast cancer diagnoses increased among middle-aged and older women during the study period.
The only other change in cancer incidence was among the youngest women, between ages 25 and 39. In that group, the number of women diagnosed with metastatic breast cancer - which has spread to the bones, brain or lungs - rose from one in 65,000 in 1976 to one in 34,000 in 2009.
Yet the overall rate of cancers in that group is still small. One in 173 women will develop breast cancer before she turns 40, said researchers, but the prognosis tends to be worse for younger patients.
The study, led by Rebecca Johnson at Seattle Children's Hospital and University of Washington, found that the rate of metastatic breast cancer in particular rose about 2 percent each year between 1976 and 2009 among younger women.
"We think that the likelihood is that since this change has been so marked over just a couple of decades, that it's something external, a modifiable lifestyle-related risk factor or perhaps an environmental toxic exposure, but we don't know what," Johnson said.
One possibility is that overeating and lack of exercise are driving up early-life metastatic breast cancer rates, she added. Or, the use of hormonal birth control could play a role.
But Johnson also pushed for more research into the potential effects of hormones in meat or plastic in bottles, for example.
Johnson's team found that the number of early breast cancer diagnoses increased among middle-aged and older women during the study period.
The only other change in cancer incidence was among the youngest women, between ages 25 and 39. In that group, the number of women diagnosed with metastatic breast cancer - which has spread to the bones, brain or lungs - rose from one in 65,000 in 1976 to one in 34,000 in 2009.
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