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March 22, 2012

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Omega-3 invigorates cancer survivors

BREAST cancer survivors who eat a healthy dose of omega-3 fats - found largely in oily fish like salmon, tuna and mackerel - may have some extra energy throughout their day, a United States study suggests.

Many people treated for cancer have lingering fatigue even years after their therapy ends, and while there's evidence that good sleep habits and regular exercise can help, other options are still needed, said researchers whose findings appeared in the Journal of Clinical Oncology.

Exactly what causes cancer survivors' long-term fatigue is unclear, but there's evidence that chronic inflammation in the body may play a role, said Rachel Ballard-Barbash of the US National Cancer Institute, who worked on the study.

"Results link higher intake of omega-3 polyunsaturated fatty acids, decreased inflammation and decreased physical aspects of fatigue," Ballard-Barbash and her colleagues wrote.

Omega-3 fats are thought to lessen inflammation, and research suggests that's especially true if the omega-3 replace some of the omega-6 fatty acids. Omega-6 fats are found in margarine, vegetable oils and an array of snack foods, sweets and fast food. Too much omega-6 is thought to promote inflammation.

For their study, Ballard-Barbash and her colleagues looked at the link between omega-3 intake and fatigue among 633 breast cancer survivors.

Overall, 42 percent of the women were considered "fatigued" three years after their diagnosis - and the problem was more common in those with higher blood levels of an inflammation-related protein called CRP.

Women who got more omega-3 in their diets had lower odds of fatigue, particularly if they used fish oil pills.

Of women who got the most omega-3 relative to omega-6, at least partly from fish oil supplements, about 23 percent were considered fatigued. That compared with 49 percent of women who did not use supplements and had the lowest omega-3 intake relative to omega-6.





 

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