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December 29, 2015

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Institute claims success for its cancer treatment

Is radiotherapy or chemotherapy the best way to treat cancer after surgery? Neither, according to a research institute in Anting, which is offering a different answer — freezing healthy cells for possible use in the future.

Shanghai Engineering Cell Therapy Research Center has begun trials where participants who join its cell storage program have blood drawn and separated into cells which are then stored in tanks of liquid nitrogen at minus 196 degrees Celsius.

In the case of a donor getting cancer one day, he or she may receive a transfusion of their own cells to boost their immunity and alleviate or cure the disease.

The center has been conducting a clinical trial for four years and claims remarkable achievements.

Among liver cancer patients at Eastern Hepatobilary Surgery Hospital who accepted cell therapy, 78 percent of those at early stage survived at least 45 months. For patients at terminal stage, nearly 35 percent survived the period. At the same time, those who took Sorafenib, a drug approved for the treatment of liver cancer, the median survival time was just six and a half months.

Cell therapy is effective in the treatment of intestinal cancer, breast cancer and melanoma, the center officials said.

“Cell therapy has smaller side effects compared to surgery, radiotherapy or chemotherapy. It not only represents a general trend of tumor treatment but is also the most promising way to cure cancer in the future,” said Wu Yajian, general manager of the center’s strategic investment department.

Several hospitals including Eastern Hepatobilary Surgery Hospital, Ningbo Cancer Center in Zhejiang Province and Hebi People’s Hospital in Henan Province have also conducted cell therapy in clinical trials, Wu said.

However, the immunocytes separated from the sample blood, which are able to induce an immune response by creating antibodies, are far from enough for clinical treatment.

That’s why the center has developed technologies to freeze, thaw, replicate and select immunocytes.




 

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