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Ruijin Hospital develops new lotion to treat skin disease
People with psoriasis, a chronic skin inflammatory disorder with frequent relapse, can have a lotion for long-term and effective use to stabilize their disease, instead of taking the traditional oral medicine or injection with big adverse reaction or expensive biological agents, local medical experts said yesterday.
The lotion, which experts from Ruijin Hospital spent 10 years for development, has been available at the market through cooperation with Shanghai Jahwa United Co.
It is the world’s first one being proven effects through strict clinical test.
Psoriasis is a common skin condition that speeds up changes the life cycle of skin cells and the extra skin cells can cause thick, silvery scales and itchy and dry patches.
There are at least 6 million people in China and 125 million people in the world with the disease, which can impact people’s life quality and there is no cure.
Dr Zheng Jie, director of Ruijin Hospital’s dermatology departments said psoriasis is a disease related immunity system, genetic reasons and environmental causes like infection and stress like anxiety, loss of sleep and severe coldness.
“About 80 percent of the cases are closely related with skin infection, which is due to damages to the skin barrier,” he said. “So we spent effects to study how to repair the skin barrier to stop the disease taking place or worsening.”
Through laboratory test, Ruijin experts found that linoleic acid and ceramide, both are fatty acids in the skin, can strengthen skin barrier. To further benefit patients, they use comprehensive components to develop the moisturizer, which Shanghai Jawha spent another six years to turn it into a lotion for ordinary use.
“A strict research conducted by Ruijin has confirmed that 58 percent of patients with psoriasis see very positive results after long-term use of the lotion,” Zheng said. “The result was published by the latest version of US-based Dermatologic Therapy, a world leading journal on skin disease.”
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