Lens-free microscope breakthrough
Print Edition
China鈥檚 Nanjing University of Science and Technology has unveiled a lens-free digital holography microscope 鈥淐yteLive鈥 that can achieve high precision and a large field of view at the same time.
Developed by a team of the university鈥檚 students, the instrument won the gold prize at the 5th China College Students鈥 鈥淚nternet+鈥 Innovation and Entrepreneurship Competition last month in east China鈥檚 Zhejiang Province.
Without a traditional optical lens, the instrument just comprises a light source and a sensor.
It is only 0.8 percent the size of a conventional microscope which is usually bulky and large, and can be easily lifted with one hand, said project leader Lu Linpeng, also a doctoral candidate at the university.
By leveraging computational microscopic imaging technologies, students developed algorithms that can reconstruct a high-resolution image based on a series of low-resolution images.
The CyteLive can offer a field of view 200 times greater than a conventional microscope, with a single image up to 100 megapixels.
It can capture 100,000 blood cells simultaneously.
Because cells are transparent, researchers usually have to stain and label cells with artificial fluorophores, which, can damage or even kill cells.
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