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December 12, 2011

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Blood platelets from stem cells

SCIENTISTS have for the first time created blood platelet cells by reprogramming stem cells derived from adult cells, offering the potential for a renewable supply of the fragile blood component.

Researchers at the Center for iPS Cell Research and Application at Kyoto University in Japan presented the data at a meeting of the American Society of Hematology showing they were able to create the cells in the laboratory and confirm they had the same life span as normal human platelets when infused in mice.

"The next step will be to conduct a trial to determine whether our platelets can function in the human body," said Dr Koji Eto, professor at the Kyoto center.

Induced pluripotent stem cells, or iPS cells, are produced by manipulating ordinary human skin or blood cells back to a state in which they are able to differentiate into different cell types.

First discovered in 2006, iPS cells were seen as perfect solution to the debate over embryonic stem cells use.





 

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