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June 29, 2010

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Fat women at risk of miscarriage from IVF

OVERWEIGHT women have a much higher risk of a miscarriage after in-vitro fertilization compared with slim women, new research says.

British doctors tracked all 318 women at a London clinic who became pregnant after having IVF from 2006 to 2009. They divided the women according to their Body Mass Index. Women who had a BMI of 18 to 24 were classified as normal. Those who had a BMI of 25 or above were considered overweight, while those above 30 were obese.

After making a statistical adjustment for factors that might have skewed the results ?? such as age, smoking and medical history ?? the researchers found overweight and obese women were much more likely to have a miscarriage as thin women. The research was presented yesterday in Rome at a meeting of the European Society of Human Reproduction and Embryology.

Among women of normal weight, 22 percent had a miscarriage. But among overweight and obese women, the risk of miscarriage was 33 percent.

Doctors have long known that heavy women are more prone to have a miscarriage and suffer other complications after becoming pregnant naturally. But there has been conflicting data over whether that was also the case after using artificial reproduction techniques.

"One of the best fertility treatments is weight loss," said Dr Richard Grazi, director of reproductive endocrinology and infertility at Maimonides Medical Center in New York, who was not linked to the study.

"With the obesity epidemic, we are constantly counseling patients to lose weight if they want to have IVF," he said. "Our goal is not only that they get pregnant, but that they stay pregnant."





 

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