Gut germs cited for Western allergies
Source: Agencies |
August 4, 2010, Wednesday
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Print Edition
Print Edition
GERMS living in the gut may cause higher rates of allergies, chronic stomach upsets and even obesity among children living in rich industrialized countries, researchers reported on Monday.
They compared intestinal bacteria between European Union children and young villagers in remote Burkina Faso, and found enough differences to help explain disparities in chronic disease and obesity.
The findings, published in the Proceedings of the National Academy of Sciences, may support the development of probiotic products to help restore the ancient balance and keep humans leaner and healthier, researchers said.
"Our results suggest that diet has a dominant role over other possible variables such as ethnicity, sanitation, hygiene, geography, and climate, in shaping the gut microbiota," Paolo Lionetti of the University of Florence in Italy and colleagues wrote.
Animal fat
"We can hypothesize that the reduction in richness we observe in EU compared with Burkina Faso children, could indicate how the consumption of sugar, animal fat, and calorie-dense foods in industrialized countries is rapidly limiting the adaptive potential of the microbiota."
The study builds on a body of evidence that human health relies heavily on the trillions of microorganisms living in and on our bodies. Only a fraction cause disease directly - many more help digest food, affect other bacteria and may influence hundreds of biological functions.
Lionetti's team found the African children had many bacteria that help break down fiber, but the European children were lacking these microbes. The ratios were similar to studies comparing the gut bacteria of lean people to obese people.
They compared intestinal bacteria between European Union children and young villagers in remote Burkina Faso, and found enough differences to help explain disparities in chronic disease and obesity.
The findings, published in the Proceedings of the National Academy of Sciences, may support the development of probiotic products to help restore the ancient balance and keep humans leaner and healthier, researchers said.
"Our results suggest that diet has a dominant role over other possible variables such as ethnicity, sanitation, hygiene, geography, and climate, in shaping the gut microbiota," Paolo Lionetti of the University of Florence in Italy and colleagues wrote.
Animal fat
"We can hypothesize that the reduction in richness we observe in EU compared with Burkina Faso children, could indicate how the consumption of sugar, animal fat, and calorie-dense foods in industrialized countries is rapidly limiting the adaptive potential of the microbiota."
The study builds on a body of evidence that human health relies heavily on the trillions of microorganisms living in and on our bodies. Only a fraction cause disease directly - many more help digest food, affect other bacteria and may influence hundreds of biological functions.
Lionetti's team found the African children had many bacteria that help break down fiber, but the European children were lacking these microbes. The ratios were similar to studies comparing the gut bacteria of lean people to obese people.
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