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New hope on prostate cancer
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A NON-SURGICAL treatment for low-risk prostate cancer in which doctors inject a light-sensitive drug derived from deep-sea bacteria into a patient’s bloodstream was shown in a trial to kill cancer cells without destroying healthy tissue.
Results of a trial in 413 patients showed that the drug, which is activated with a laser to destroy tumor tissue in the prostate, was so effective that half the patients went into remission, compared with 13.5 percent in a control group.
“These results are excellent news for men with early localized prostate cancer, offering a treatment that can kill cancer without removing or destroying the prostate,” said Mark Emberton, a University College London consultant urologist who led the trial. “This is truly a huge leap forward.”
The vascular-targeted photodynamic therapy treatment was developed by scientists at the Weizmann Institute of Science in Israel in collaboration with a biotech firm.
The light-sensitive drug used, called WST11, is derived from bacteria found at the bottom of the ocean. To survive with very little sunlight, they convert light into energy with incredible efficiency, the team said in a study published in the journal Lancet Oncology. WST111 releases free radicals to kill surrounding cells when activated by laser.
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