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September 22, 2010

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Stem cells, gene chips lead Nobel predictions

RESEARCHERS who discovered stem cells and the appetite hormone leptin, who proposed that dark energy is helping the universe expand and who developed "gene chips" are named in the 2010 Thomson Reuters predictions to win Nobel Prizes for medicine, physics and chemistry.

Thomson Reuters expert David Pendlebury's forecast is made using the company's "Web of Knowledge" data on how often a researcher's published papers are used and cited - used as a basis for further research - by other scientists. Every year at least one of the picks from one of his annual lists has won a Nobel prize.

"Some people perform outstandingly differently from so-called ordinary researchers," Pendlebury, of Thomson Reuters Healthcare & Science division, said in a telephone interview. "People who win the Nobel prize publish about five times as much as the average scientist and are cited 20 times as often as the average scientist."

For the Nobel prize for Physiology or Medicine, to be announced on October 4, Pendlebury has chosen three possible teams this year.

They are Douglas Coleman of Jackson Laboratory in Bar Harbor, Maine, and Jeffrey Friedman of Rockefeller University in New York, for their work discovering leptin, a hormone linked to appetite and obesity.

Nobels often go to groups of three researchers and Pendlebury also picks Ernest McCulloch and James Till of the Ontario Cancer Institute in Toronto, who first discovered stem cells in bone marrow in the early 1960s and Shinya Yamanaka of Japan's Kyoto University and the Gladstone Institute of Cardiovascular Disease in San Francisco, who discovered in 2006 how to make induced pluripotent stem cells or iPS cells from ordinary skin cells.

For the physics prize, to be announced on Tuesday, October 5, Pendlebury points to Saul Perlmutter of the University of California Berkeley, Adam Riess of Johns Hopkins University in Baltimore and Brian Schmidt of Australian National University for discoveries of about how the universe is expanding and how dark energy might permeate the whole universe and affect this.

Pendlebury also names Stephen Lippard of the Massachusetts Institute of Technology, who found a way to make platinum disrupt DNA, the basis of a family of cancer drugs that use the metal.





 

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