Chinese team offers hope for the blind
Print Edition
Chinese researchers have used iPS cells to regenerate retina, which holds the potential to develop new therapies for some blinding diseases such as retinal degeneration.
The iPS cells are a type of pluripotent stem cell artificially derived from a non-pluripotent cell. It can be induced to have the same genetic information as early embryonic cells.
Researchers from China鈥檚 Central South University made iPS cells from somatic cells in the patients鈥 urine or blood and induced the iPS cells to differentiate into RPE cells, a layer of cells in the back of the eye.
According to the research published in the journal Acta Biomaterialia, the RPE cells can form an ultra-thin layer of structure similar to the retina.
In future studies, the researchers plan to transplant the structure behind the patient鈥檚 retina to see if it can fix the patient鈥檚 vision.
Since the iPS cells come from the patient鈥檚 own cells, rejection of the transplantat is avoided.
Retinal degeneration, which may cause blindness, is one of the most common eye diseases in people over 50.
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